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Total Synthesis of Brevisamide

[Image: see text] The second total synthesis of Brevisamide, a marine cyclic ether alkaloid from Karenia brevis is reported. This streamlined synthesis proceeds in 21 steps, 14 steps longest linear sequence, in 5.2% overall yield and features a key SmI(2) reductive cyclization step to access the tet...

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Détails bibliographiques
Auteurs principaux: Fadeyi, Olugbeminiyi O., Lindsley, Craig W.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838230/
https://ncbi.nlm.nih.gov/pubmed/19639953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol9015755
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