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Rapid, General Access to Chiral β-Fluoroamines and β, β-Difluoroamines via Organocatalysis
[Image: see text] A rapid, general route to enantiopure β-fluoroamines and β,β-difluoroamines has been developed employing organocatalysis in both a two-pot and a one-pot procedure. Both chemical yields (64–82%) and enantioselectivity (94–98% ee) were excellent and represent a significant improvemen...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3192010/ https://ncbi.nlm.nih.gov/pubmed/19159275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol802930q |
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