Lataa...
Catalytic Asymmetric Mannich Reactions with Fluorinated Aromatic Ketones: Efficient Access to Chiral β-Fluoroamines
Herein, we report a Zn-Prophenol catalyzed Mannich reaction using fluorinated aromatic ketones as nucleophilic partners for the direct enantio- and diastereoselective construction of β–fluoroamine motifs featuring a fluorinated tetrasubstituted carbon. The reaction can be run on a gram-scale with a...
Tallennettuna:
| Julkaisussa: | Angew Chem Int Ed Engl |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4837127/ https://ncbi.nlm.nih.gov/pubmed/26609784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201509719 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|