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Catalytic Asymmetric Synthesis of Chiral γ-Amino Ketones via Umpolung Reactions of Imines

The first direct catalytic asymmetric synthesis of γ-amino ketones was realized by the development of a highly diastereoselective and enantioselective C-C bond-forming umpolung reaction of imines and enones under the catalysis of a new cinchona alkaloid-derived phase-transfer catalyst. In a loading...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Hu, Lin, Wu, Yongwei, Li, Zhe, Deng, Li
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654742/
https://ncbi.nlm.nih.gov/pubmed/27960300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b09754
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