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Asymmetric Synthesis of α-Amino 1,3-Dithianes via Chiral N-Phosphonyl Imine-based Umpolung Reaction

A series of α-amino-1,3-dithianes have been synthesized via the asymmetric Umpolung reaction of 2-lithio-1,3-dithianes with chiral N-phosphonyl imines in good chemical yields (up to 82%) and good to excellent diastereoselectivities (>99:1). The addition manner by which chiral N-phosphonyl imines...

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Autors principals: Kattamuri, Padmanabha V., Ai, Teng, Pindi, Suresh, Sun, Yinwei, Gu, Peng, Shi, Min, Li, Guigen
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3074014/
https://ncbi.nlm.nih.gov/pubmed/21405041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo200070d
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