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Highly Diastereoselective and General Synthesis of Primary β-Fluoroamines

[Image: see text] A short, high yielding protocol has been developed for the highly diastereoselective (dr >20:1) and general synthesis of primary β-fluoroamines by the enantioselective α-fluorination of aldehydes, conversion into the N-sulfinyl aldimine, nucleophilic addition of various organome...

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Hlavní autoři: Schulte, Michael L., Lindsley, Craig W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196525/
https://ncbi.nlm.nih.gov/pubmed/21942742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol202415j
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