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A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function
BACKGROUND: Overexpression of mutant copper/zinc superoxide dismutase (SOD1) in rodents has provided useful models for studying the pathogenesis of amyotrophic lateral sclerosis (ALS). Microglia have been shown to contribute to ALS disease progression in these models, although the mechanism of this...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191510/ https://ncbi.nlm.nih.gov/pubmed/21943126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-12-91 |
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