An in vitro screening cascade to identify neuroprotective antioxidants in ALS

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease, characterized by progressive dysfunction and death of motor neurons. Although evidence for oxidative stress in ALS pathogenesis is well described, antioxidants have generally shown poor efficacy in animal models and hum...

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Detalhes bibliográficos
Main Authors: Barber, Siân C., Higginbottom, Adrian, Mead, Richard J., Barber, Stuart, Shaw, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2009
Assuntos:
Original Contribution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742740/
https://ncbi.nlm.nih.gov/pubmed/19439221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.01.019
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