Neuroprotection and Reduced Proliferation of Microglia in Ribavirin-Treated Bornavirus-Infected Rats

In a rat model of Borna disease, intracerebral ribavirin caused clinical improvement without changes in virus titer or nucleic acid. Levels of microglia and infiltrating CD4 and CD8 cells were decreased, despite increases in mRNAs encoding interleukin-1β (IL-1β), IL-10, and gamma interferon in the b...

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Detalhes bibliográficos
Main Authors: Solbrig, Marylou V., Schlaberg, Robert, Briese, Thomas, Horscroft, Nigel, Lipkin, W. Ian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127284/
https://ncbi.nlm.nih.gov/pubmed/12069992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.7.2287-2291.2002
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