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Wild-type but not mutant SOD1 transgenic astrocytes promote the efficient generation of motor neuron progenitors from mouse embryonic stem cells

BACKGROUND: The efficient derivation of mature (Hb9+) motor neurons from embryonic stem cells is a sought-after goal in the understanding, and potential treatment, of motor neuron diseases. Conditions that promote the robust generation of motor neuron progenitors from embryonic stem cells and that p...

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Detalhes bibliográficos
Main Authors: Christou, Yiota A, Ohyama, Kyoji, Placzek, Marysia, Monk, Peter N, Shaw, Pamela J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853012/
https://ncbi.nlm.nih.gov/pubmed/24134124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-126
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