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Modulation of SOD1 Subcellular Localization by Transfection with Wild- or Mutant-type SOD1 in Primary Neuron and Astrocyte Cultures from ALS Mice

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disorder characterized by selective degeneration of motor neurons. Mutant superoxide dismutase 1 (SOD1) is often found as aggregates in the cytoplasm in motor neurons of various mouse models and familial ALS patients. The interplay between...

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Detalhes bibliográficos
Publicado no:Exp Neurobiol
Main Authors: Lee, Do-Yeon, Jeon, Gye Sun, Shim, Yu-mi, Seong, Seung-Yong, Lee, Kwang-Woo, Sung, Jung-Joon
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society for Brain and Neural Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580750/
https://ncbi.nlm.nih.gov/pubmed/26412972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5607/en.2015.24.3.226
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