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Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1

Amyotrophic lateral sclerosis (ALS) is caused by the progressive degeneration of motor neurons. Mutations in the Cu/Zn superoxide dismutase (SOD1) are found in about 20% of patients with familial ALS. Mutant SOD1 causes motor neuron death through an acquired toxic property. Although the molecular me...

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Bibliografiske detaljer
Main Authors: Vargas, Marcelo R., Pehar, Mariana, Díaz-Amarilla, Pablo J., Beckman, Joseph S., Barbeito, Luis
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048747/
https://ncbi.nlm.nih.gov/pubmed/18683239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21797
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