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Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1
Amyotrophic lateral sclerosis (ALS) is caused by the progressive degeneration of motor neurons. Mutations in the Cu/Zn superoxide dismutase (SOD1) are found in about 20% of patients with familial ALS. Mutant SOD1 causes motor neuron death through an acquired toxic property. Although the molecular me...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048747/ https://ncbi.nlm.nih.gov/pubmed/18683239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.21797 |
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