Two Distinct Aspects of Coupling between Gα(i) Protein and G Protein-activated K(+) Channel (GIRK) Revealed by Fluorescently Labeled Gα(i3) Protein Subunits

G protein-activated K(+) channels (Kir3 or GIRK) are activated by direct interaction with Gβγ. Gα is essential for specific signaling and regulates basal activity of GIRK (I(basal)) and kinetics of the response elicited by activation by G protein-coupled receptors (I(evoked)). These regulations are...

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Detaylı Bibliyografya
Asıl Yazarlar: Berlin, Shai, Tsemakhovich, Vladimir A., Castel, Ruth, Ivanina, Tatiana, Dessauer, Carmen W., Keren-Raifman, Tal, Dascal, Nathan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190912/
https://ncbi.nlm.nih.gov/pubmed/21795707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.271056
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