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Autoregulated Splicing of muscleblind-like 1 (MBNL1) Pre-mRNA
Muscleblind-like 1 (MBNL1) is a splicing factor whose improper cellular localization is a central component of myotonic dystrophy. In myotonic dystrophy, the lack of properly localized MBNL1 leads to missplicing of many pre-mRNAs. One of these events is the aberrant inclusion of exon 5 within the MB...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3190765/ https://ncbi.nlm.nih.gov/pubmed/21832083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236547 |
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