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Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1
Muscleblind-like (MBNL) proteins, regulators of developmentally programmed alternative splicing, harbor tandem CCCH zinc-finger (ZnF) domains that target pre-mRNAs containing YGCU(U/G)Y sequence elements (where Y is a pyrimidine). In myotonic dystrophy, reduced levels of MBNL proteins lead to aberra...
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| Gepubliceerd in: | Nat Struct Mol Biol |
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| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2008
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689322/ https://ncbi.nlm.nih.gov/pubmed/19043415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1519 |
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