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Muscleblind-like 1 (Mbnl1) regulates pre-mRNA alternative splicing during terminal erythropoiesis

The scope and roles of regulated isoform gene expression during erythroid terminal development are poorly understood. We identified hundreds of differentiation-associated isoform changes during terminal erythropoiesis. Sequences surrounding cassette exons of skipped exon events are enriched for moti...

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Hlavní autoři: Cheng, Albert W., Shi, Jiahai, Wong, Piu, Luo, Katherine L., Trepman, Paula, Wang, Eric T., Choi, Heejo, Burge, Christopher B., Lodish, Harvey F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110662/
https://ncbi.nlm.nih.gov/pubmed/24869935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-12-542209
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