Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes

It is unclear how epigenetic changes regulate the induction of erythroid-specific genes during terminal erythropoiesis. Here we use global mRNA sequencing (mRNA-seq) and chromatin immunoprecipitation coupled to high-throughput sequencing (CHIP-seq) to investigate the changes that occur in mRNA level...

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Detalhes bibliográficos
Main Authors: Wong, Piu, Hattangadi, Shilpa M., Cheng, Albert W., Frampton, Garrett M., Young, Richard A., Lodish, Harvey F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204918/
https://ncbi.nlm.nih.gov/pubmed/21860024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-341404
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