Autoregulated Splicing of muscleblind-like 1 (MBNL1) Pre-mRNA

Muscleblind-like 1 (MBNL1) is a splicing factor whose improper cellular localization is a central component of myotonic dystrophy. In myotonic dystrophy, the lack of properly localized MBNL1 leads to missplicing of many pre-mRNAs. One of these events is the aberrant inclusion of exon 5 within the MB...

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Main Authors: Gates, Devika P., Coonrod, Leslie A., Berglund, J. Andrew
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
主題:
RNA
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190765/
https://ncbi.nlm.nih.gov/pubmed/21832083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236547
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