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Role of hypoxia-inducible factor-1α in angiogenic–osteogenic coupling

Angiogenesis and osteogenesis are tightly coupled during bone development and regeneration. The vasculature supplies oxygen to developing and regenerating bone and also delivers critical signals to the stroma that stimulate mesenchymal cell specification to promote bone formation. Recent studies sug...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Riddle, Ryan C., Khatri, Richa, Schipani, Ernestina, Clemens, Thomas L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189695/
https://ncbi.nlm.nih.gov/pubmed/19415227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0477-9
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