Role of hypoxia-inducible factor-1α in angiogenic–osteogenic coupling

Angiogenesis and osteogenesis are tightly coupled during bone development and regeneration. The vasculature supplies oxygen to developing and regenerating bone and also delivers critical signals to the stroma that stimulate mesenchymal cell specification to promote bone formation. Recent studies sug...

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Bibliografiske detaljer
Main Authors: Riddle, Ryan C., Khatri, Richa, Schipani, Ernestina, Clemens, Thomas L.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189695/
https://ncbi.nlm.nih.gov/pubmed/19415227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0477-9
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https://ncbi.nlm.nih.gov/pmc/articles/PMC3189695/
https://ncbi.nlm.nih.gov/pubmed/19415227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0477-9