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Role of hypoxia-inducible factor-1α in angiogenic–osteogenic coupling

Angiogenesis and osteogenesis are tightly coupled during bone development and regeneration. The vasculature supplies oxygen to developing and regenerating bone and also delivers critical signals to the stroma that stimulate mesenchymal cell specification to promote bone formation. Recent studies sug...

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Autors principals: Riddle, Ryan C., Khatri, Richa, Schipani, Ernestina, Clemens, Thomas L.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189695/
https://ncbi.nlm.nih.gov/pubmed/19415227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0477-9
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