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Role of hypoxia-inducible factor-1α in angiogenic–osteogenic coupling

Angiogenesis and osteogenesis are tightly coupled during bone development and regeneration. The vasculature supplies oxygen to developing and regenerating bone and also delivers critical signals to the stroma that stimulate mesenchymal cell specification to promote bone formation. Recent studies sug...

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Detalhes bibliográficos
Main Authors: Riddle, Ryan C., Khatri, Richa, Schipani, Ernestina, Clemens, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189695/
https://ncbi.nlm.nih.gov/pubmed/19415227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-009-0477-9
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