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Role of HIF-1α in skeletal development

Angiogenesis and osteogenesis are tightly coupled during bone development and regeneration. Mesenchymal cells in the developing stroma elicit angiogenic signals to recruit new blood vessels into bone. Reciprocal signals, likely emanating from the incoming vascular endothelium, stimulate mesenchymal...

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Bibliographic Details
Main Authors: Wan, Chao, Shao, Jin, Gilbert, Shawn R., Riddle, Ryan C., Long, Fanxin, Johnson, Randall S., Schipani, Ernestina, Clemens, Thomas L.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047468/
https://ncbi.nlm.nih.gov/pubmed/20392254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2009.05238.x
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