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HIF-1α and growth plate development: what we really know

Adaptation to low oxygen tension or hypoxia is a critical event in development and tissue homeostasis. Studies by us and others have shown that the fetal growth plate is an avascular tissue with a gradient of oxygenation, and the transcription factor hypoxia-inducible factor-1α (HIF-1α) is essential...

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Publicado en:Bonekey Rep
Main Authors: Schipani, Ernestina, Mangiavini, Laura, Merceron, Christophe
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549921/
https://ncbi.nlm.nih.gov/pubmed/26331009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bonekey.2015.99
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