A Panel of IgG1 b12 Variants with Selectively Diminished or Enhanced Affinity for Fcγ Receptors To Define the Role of Effector Functions in Protection against HIV

Passive transfer of neutralizing antibodies is effective in protecting rhesus macaques against simian/human immunodeficiency virus (SHIV) challenge. In addition to neutralization, effector functions of the crystallizable fragment (Fc) of antibodies are involved in antibody-mediated protection agains...

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Autors principals: Moldt, Brian, Schultz, Niccole, Dunlop, D. Cameron, Alpert, Michael D., Harvey, Jackson D., Evans, David T., Poignard, Pascal, Hessell, Ann J., Burton, Dennis R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187489/
https://ncbi.nlm.nih.gov/pubmed/21849450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05541-11
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