Affinity of human IgG subclasses to mouse Fc gamma receptors

Human IgG is the main antibody class used in antibody therapies because of its efficacy and longer half-life, which are completely or partly due to FcγR-mediated functions of the molecules. Preclinical testing in mouse models are frequently performed using human IgG, but no detailed information on b...

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Detalles Bibliográficos
Publicado en:MAbs
Main Authors: Dekkers, Gillian, Bentlage, Arthur E. H., Stegmann, Tamara C., Howie, Heather L., Lissenberg-Thunnissen, Suzanne, Zimring, James, Rispens, Theo, Vidarsson, Gestur
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Short Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5524164/
https://ncbi.nlm.nih.gov/pubmed/28463043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1323159
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