IgG Subclass Determines Suppression Versus Enhancement of Humoral Alloimmunity to Kell RBC Antigens in Mice

It has long been appreciated that immunoglobulins are not just the effector endpoint of humoral immunity, but rather have a complex role in regulating antibody responses themselves. Donor derived anti-RhD IgG has been used for over 50 years as an immunoprophylactic to prevent maternal alloimmunizati...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Shinde, Paurvi, Howie, Heather L., Stegmann, Tamara C., Hay, Ariel M., Waterman, Hayley R., Szittner, Zoltan, Bentlage, Arthur E. H., Kapp, Linda, Lissenberg-Thunnissen, Suzanne N., Dekkers, Gillian, Schasfoort, Richard B. M., Ratcliffe, Sarah J., Smolkin, Mark E., Vidarsson, Gestur, van der Schoot, C. Ellen, Hudson, Krystalyn E., Zimring, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378678/
https://ncbi.nlm.nih.gov/pubmed/32765523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01516
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