IgG Subclass Determines Suppression Versus Enhancement of Humoral Alloimmunity to Kell RBC Antigens in Mice

It has long been appreciated that immunoglobulins are not just the effector endpoint of humoral immunity, but rather have a complex role in regulating antibody responses themselves. Donor derived anti-RhD IgG has been used for over 50 years as an immunoprophylactic to prevent maternal alloimmunizati...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Shinde, Paurvi, Howie, Heather L., Stegmann, Tamara C., Hay, Ariel M., Waterman, Hayley R., Szittner, Zoltan, Bentlage, Arthur E. H., Kapp, Linda, Lissenberg-Thunnissen, Suzanne N., Dekkers, Gillian, Schasfoort, Richard B. M., Ratcliffe, Sarah J., Smolkin, Mark E., Vidarsson, Gestur, van der Schoot, C. Ellen, Hudson, Krystalyn E., Zimring, James C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378678/
https://ncbi.nlm.nih.gov/pubmed/32765523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01516
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