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IgG Subclasses and Allotypes: From Structure to Effector Functions

Of the five immunoglobulin isotypes, immunoglobulin G (IgG) is most abundant in human serum. The four subclasses, IgG1, IgG2, IgG3, and IgG4, which are highly conserved, differ in their constant region, particularly in their hinges and upper CH2 domains. These regions are involved in binding to both...

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Detalhes bibliográficos
Main Authors: Vidarsson, Gestur, Dekkers, Gillian, Rispens, Theo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202688/
https://ncbi.nlm.nih.gov/pubmed/25368619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00520
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