MS-Based Allotype-Specific Analysis of Polyclonal IgG-Fc N-Glycosylation

Current approaches to study glycosylation of polyclonal human immunoglobulins G (IgG) usually imply protein digestion or glycan release. While these approaches allow in-depth characterization, they also result in a loss of valuable information regarding certain subclasses, allotypes and co-occuring...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Sénard, Thomas, Gargano, Andrea F. G., Falck, David, de Taeye, Steven W., Rispens, Theo, Vidarsson, Gestur, Wuhrer, Manfred, Somsen, Govert W., Domínguez-Vega, Elena
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7472933/
https://ncbi.nlm.nih.gov/pubmed/32973813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02049
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