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Novel Concepts of Altered Immunoglobulin G Galactosylation in Autoimmune Diseases
The composition of the conserved N297 glycan in immunoglobulin G (IgG) has been shown to affect antibody effector functions via C1q of the complement system and Fc gamma receptors (FcγR) on immune cells. Changes in the general levels of IgG-glycoforms, such as lowered total IgG galactosylation obser...
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| Опубликовано в: : | Front Immunol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Frontiers Media S.A.
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5867308/ https://ncbi.nlm.nih.gov/pubmed/29616041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00553 |
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