A Panel of IgG1 b12 Variants with Selectively Diminished or Enhanced Affinity for Fcγ Receptors To Define the Role of Effector Functions in Protection against HIV

Passive transfer of neutralizing antibodies is effective in protecting rhesus macaques against simian/human immunodeficiency virus (SHIV) challenge. In addition to neutralization, effector functions of the crystallizable fragment (Fc) of antibodies are involved in antibody-mediated protection agains...

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Main Authors: Moldt, Brian, Schultz, Niccole, Dunlop, D. Cameron, Alpert, Michael D., Harvey, Jackson D., Evans, David T., Poignard, Pascal, Hessell, Ann J., Burton, Dennis R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187489/
https://ncbi.nlm.nih.gov/pubmed/21849450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05541-11
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