Balanced Interactions between Lyn, the p85α Regulatory Subunit of Class I(A) Phosphatidylinositol-3-Kinase, and SHIP Are Essential for Mast Cell Growth and Maturation

The growth and maturation of bone marrow-derived mast cells (BMMCs) from precursors are regulated by coordinated signals from multiple cytokine receptors, including KIT. While studies conducted using mutant forms of these receptors lacking the binding sites for Src family kinases (SFKs) and phosphat...

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Hlavní autoři: Ma, Peilin, Vemula, Sasidhar, Munugalavadla, Veerendra, Chen, Jinbiao, Sims, Emily, Borneo, Jovencio, Kondo, Takako, Ramdas, Baskar, Mali, Raghuveer Singh, Li, Shuo, Hashino, Eri, Takemoto, Clifford, Kapur, Reuben
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187372/
https://ncbi.nlm.nih.gov/pubmed/21791602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05750-11
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