Organoid technologies meet genome engineering

Por Nie, Jing, Hashino, Eri
Publicado no EMBO Rep (2017)

The histone demethylase LSD1 regulates inner ear progenitor differentiation through interactions with Pax2 and the NuRD repressor complex

Por Patel, Dharmeshkumar, Shimomura, Atsushi, Majumdar, Sreeparna, Holley, Matthew C., Hashino, Eri
Publicado no PLoS One (2018)

Sonic hedgehog and retinoic acid synergistically promote sensory fate specification from bone marrow-derived pluripotent stem cells

Por Kondo, Takako, Johnson, Scott A., Yoder, Mervin C., Romand, Raymond, Hashino, Eri
Publicado em 2005

Dynamic expression of retinoic acid synthesizing and metabolizing enzymes in the developing mouse inner ear

Por Romand, Raymond, Kondo, Takako, Fraulob, Valérie, Petkovich, Martin, Dollé, Pascal, Hashino, Eri
Publicado em 2006

Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture

Por Koehler, Karl R., Mikosz, Andrew M., Molosh, Andrei I., Patel, Dharmeshkumar, Hashino, Eri
Publicado em 2013

Tlx3 Promotes Glutamatergic Neuronal Subtype Specification through Direct Interactions with the Chromatin Modifier CBP

Por Shimomura, Atsushi, Patel, Dharmeshkumar, Wilson, Sarah M., Koehler, Karl R., Khanna, Rajesh, Hashino, Eri
Publicado no PLoS One (2015)

Functional development of mechanosensitive hair cells in stem cell-derived organoids parallels native vestibular hair cells

Por Liu, Xiao-Ping, Koehler, Karl R., Mikosz, Andrew M., Hashino, Eri, Holt, Jeffrey R.
Publicado no Nat Commun (2016)

Extended passaging increases the efficiency of neural differentiation from induced pluripotent stem cells

Por Koehler, Karl R, Tropel, Philippe, Theile, Jonathan W, Kondo, Takako, Cummins, Theodore R, Viville, Stéphane, Hashino, Eri
Publicado em 2011

Modulation of Wnt Signaling Enhances Inner Ear Organoid Development in 3D Culture

Por DeJonge, Rachel E., Liu, Xiao-Ping, Deig, Christopher R., Heller, Stefan, Koehler, Karl R., Hashino, Eri
Publicado no PLoS One (2016)

Generation of inner ear organoids with functional hair cells from human pluripotent stem cells

Por Koehler, Karl R., Nie, Jing, Longworth-Mills, Emma, Liu, Xiao-Ping, Lee, Jiyoon, Holt, Jeffrey R., Hashino, Eri
Publicado no Nat Biotechnol (2017)

Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells

Por Kondo, Takako, Sheets, Patrick L., Zopf, David A., Aloor, Heather L., Cummins, Theodore R., Chan, Rebecca J., Hashino, Eri
Publicado em 2008

Wnt signaling promotes neuronal differentiation from mesenchymal stem cells through activation of Tlx3

Por Kondo, Takako, Matsuoka, Akihiro J., Shimomura, Atsushi, Koehler, Karl R., Chan, Rebecca J., Miller, Josef M., Srour, Edward F., Hashino, Eri
Publicado em 2011

Class I(A) PI3Kinase Regulatory Subunit, p85α, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes

Por Krishnan, Subha, Mali, Raghuveer Singh, Koehler, Karl R., Vemula, Sasidhar, Chatterjee, Anindya, Ghosh, Joydeep, Ramdas, Baskar, Ma, Peilin, Hashino, Eri, Kapur, Reuben
Publicado em 2012

ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53

Por Vemula, Sasidhar, Shi, Jianjian, Mali, Raghuveer Singh, Ma, Peilin, Liu, Yan, Hanneman, Philip, Koehler, Karl R., Hashino, Eri, Wei, Lei, Kapur, Reuben
Publicado em 2012

Balanced Interactions between Lyn, the p85α Regulatory Subunit of Class I(A) Phosphatidylinositol-3-Kinase, and SHIP Are Essential for Mast Cell Growth and Maturation

Por Ma, Peilin, Vemula, Sasidhar, Munugalavadla, Veerendra, Chen, Jinbiao, Sims, Emily, Borneo, Jovencio, Kondo, Takako, Ramdas, Baskar, Mali, Raghuveer Singh, Li, Shuo, Hashino, Eri, Takemoto, Clifford, Kapur, Reuben
Publicado em 2011

Increased c-Jun Expression and Reduced GATA2 Expression Promote Aberrant Monocytic Differentiation Induced by Activating PTPN11 Mutants

Por Yang, Zhenyun, Kondo, Takako, Voorhorst, Cara S., Nabinger, Sarah C., Ndong, Leila, Yin, Fuqin, Chan, Edward M., Yu, Menggang, Würstlin, Oliver, Kratz, Christian P., Niemeyer, Charlotte M., Flotho, Christian, Hashino, Eri, Chan, Rebecca J.
Publicado em 2009