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Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture

The inner ear contains sensory epithelia that detect head movements, gravity and sound. It is unclear how to derive these sensory epithelia from pluripotent stem cells, a process which will be critical for modeling inner ear disorders or developing cell-based therapies for profound hearing loss and...

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Detalhes bibliográficos
Main Authors: Koehler, Karl R., Mikosz, Andrew M., Molosh, Andrei I., Patel, Dharmeshkumar, Hashino, Eri
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3739998/
https://ncbi.nlm.nih.gov/pubmed/23842490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12298
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