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Generation of inner ear organoids with functional hair cells from human pluripotent stem cells

Human inner ear tissue derived from pluripotent stem cells could provide a powerful platform for drug discovery or a source of sound- or motion-sensing cells for patients with hearing loss or balance dysfunction. Here we report a method for differentiating human pluripotent stem cells to inner ear o...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Koehler, Karl R., Nie, Jing, Longworth-Mills, Emma, Liu, Xiao-Ping, Lee, Jiyoon, Holt, Jeffrey R., Hashino, Eri
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5462862/
https://ncbi.nlm.nih.gov/pubmed/28459451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3840
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