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Balanced Interactions between Lyn, the p85α Regulatory Subunit of Class I(A) Phosphatidylinositol-3-Kinase, and SHIP Are Essential for Mast Cell Growth and Maturation
The growth and maturation of bone marrow-derived mast cells (BMMCs) from precursors are regulated by coordinated signals from multiple cytokine receptors, including KIT. While studies conducted using mutant forms of these receptors lacking the binding sites for Src family kinases (SFKs) and phosphat...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187372/ https://ncbi.nlm.nih.gov/pubmed/21791602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05750-11 |
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