Class I(A) PI3Kinase Regulatory Subunit, p85α, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes

Stem cell factor (SCF) mediated KIT receptor activation plays a pivotal role in mast cell growth, maturation and survival. However, the signaling events downstream from KIT are poorly understood. Mast cells express multiple regulatory subunits of class 1(A) PI3Kinase (PI3K) including p85α, p85β, p50...

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Bibliographische Detailangaben
Hauptverfasser: Krishnan, Subha, Mali, Raghuveer Singh, Koehler, Karl R., Vemula, Sasidhar, Chatterjee, Anindya, Ghosh, Joydeep, Ramdas, Baskar, Ma, Peilin, Hashino, Eri, Kapur, Reuben
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251560/
https://ncbi.nlm.nih.gov/pubmed/22238586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028979
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