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Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation
Nitric oxide (NO) stimulates cGMP synthesis by activating its intracellular receptor, soluble guanylyl cyclase (sGC). It is a currently prevailing concept that No and cGMP inhibits platelet function. However, the data supporting the inhibitory role of NO/sGC/cGMP in platelets have been obtained eith...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186338/ https://ncbi.nlm.nih.gov/pubmed/21803853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-341107 |
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