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Dynamical Allosterism in the Mechanism of Action of DNA Mismatch Repair Protein MutS
The multidomain protein Thermus aquaticus MutS and its prokaryotic and eukaryotic homologs recognize DNA replication errors and initiate mismatch repair. MutS actions are fueled by ATP binding and hydrolysis, which modulate its interactions with DNA and other proteins in the mismatch-repair pathway....
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183814/ https://ncbi.nlm.nih.gov/pubmed/21961599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2011.08.039 |
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