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The effects of nucleotides on MutS-DNA binding kinetics clarify the role of MutS ATPase activity in mismatch repair

MutS protein initiates mismatch repair with recognition of a non-Watson-Crick base pair or base insertion/deletion site in DNA, and its interactions with DNA are modulated by ATPase activity. Here we present a kinetic analysis of these interactions, including the effects of ATP binding and hydrolysi...

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書誌詳細
主要な著者: Jacobs-Palmer, Emily, Hingorani, Manju M.
フォーマット: Artigo
言語:Inglês
出版事項: 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941710/
https://ncbi.nlm.nih.gov/pubmed/17207499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.11.092
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