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Dynamics of MutS–Mismatched DNA Complexes Are Predictive of Their Repair Phenotypes

[Image: see text] MutS recognizes base–base mismatches and base insertions/deletions (IDLs) in newly replicated DNA. Specific interactions between MutS and these errors trigger a cascade of protein–protein interactions that ultimately lead to their repair. The inability to explain why different DNA...

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Autors principals: DeRocco, Vanessa C., Sass, Lauryn E., Qiu, Ruoyi, Weninger, Keith R., Erie, Dorothy A.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985873/
https://ncbi.nlm.nih.gov/pubmed/24588663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401429b
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