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GDE2 regulates subtype specific motor neuron generation through inhibition of Notch signaling
The specification of spinal interneuron and motor neuron identities initiates within progenitor cells, while motor neuron subtype diversification is regulated by hierarchical transcriptional programs implemented postmitotically. Here, we find that mice lacking GDE2, a six-transmembrane protein that...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3183458/ https://ncbi.nlm.nih.gov/pubmed/21943603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.07.028 |
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