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GDE2 promotes neurogenesis by glycosylphosphatidylinositol-anchor cleavage of RECK
The six-transmembrane protein glycerophosphodiester phosphodiesterase 2 (GDE2) induces spinal motor neuron differentiation by inhibiting Notch signaling in adjacent motor neuron progenitors. GDE2 function requires activity of its extracellular domain that shares homology with glycerophosphodiester p...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644959/ https://ncbi.nlm.nih.gov/pubmed/23329048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1231921 |
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