GDE2 is essential for neuronal survival in the postnatal mammalian spinal cord

BACKGROUND: Glycerophosphodiester phosphodiesterase 2 (GDE2) is a six-transmembrane protein that cleaves glycosylphosphatidylinositol (GPI) anchors to regulate GPI-anchored protein activity at the cell surface. In the developing spinal cord, GDE2 utilizes its enzymatic function to regulate the produ...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Cave, Clinton, Park, Sungjin, Rodriguez, Marianeli, Nakamura, Mai, Hoke, Ahmet, Pletnikov, Mikhail, Sockanathan, Shanthini
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244531/
https://ncbi.nlm.nih.gov/pubmed/28103900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-017-0148-1
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