The distribution and function of GDE2, a regulator of spinal motor neuron survival, are disrupted in Amyotrophic Lateral Sclerosis

Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that affects the viability of upper and lower motor neurons. Current options for treatment are limited, necessitating deeper understanding of the mechanisms underlying ALS pathogenesis. Glycerophosphodiester phosphodie...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Anna Westerhaus, Thea Joseph, Alison J. Meyers, Yura Jang, Chan Hyun Na, Clinton Cave, Shanthini Sockanathan
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-05-01
Colecção:Acta Neuropathologica Communications
Assuntos:
GDE2
Motor neuron
Neurodegeneration
GPI-anchored proteins
ALS
Acesso em linha:https://doi.org/10.1186/s40478-022-01376-x
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados