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The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox dependent activation of GDE2
The six-transmembrane protein GDE2 comprises a new signaling system that controls the onset and progression of spinal motor neuron differentiation through extracellular glycerophosphodiester phosphodiesterase metabolism. However, the mechanisms that regulate its activity are unknown. Here we show th...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748999/ https://ncbi.nlm.nih.gov/pubmed/19766572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.06.042 |
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