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The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox dependent activation of GDE2

The six-transmembrane protein GDE2 comprises a new signaling system that controls the onset and progression of spinal motor neuron differentiation through extracellular glycerophosphodiester phosphodiesterase metabolism. However, the mechanisms that regulate its activity are unknown. Here we show th...

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Main Authors: Yan, Ye, Sabharwal, Priyanka, Rao, Meenakshi, Sockanathan, Shanthini
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748999/
https://ncbi.nlm.nih.gov/pubmed/19766572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.06.042
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