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The antioxidant enzyme Prdx1 controls neuronal differentiation by thiol-redox dependent activation of GDE2

The six-transmembrane protein GDE2 comprises a new signaling system that controls the onset and progression of spinal motor neuron differentiation through extracellular glycerophosphodiester phosphodiesterase metabolism. However, the mechanisms that regulate its activity are unknown. Here we show th...

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Detalhes bibliográficos
Main Authors: Yan, Ye, Sabharwal, Priyanka, Rao, Meenakshi, Sockanathan, Shanthini
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748999/
https://ncbi.nlm.nih.gov/pubmed/19766572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.06.042
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