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GDE2 regulates subtype specific motor neuron generation through inhibition of Notch signaling

The specification of spinal interneuron and motor neuron identities initiates within progenitor cells, while motor neuron subtype diversification is regulated by hierarchical transcriptional programs implemented postmitotically. Here, we find that mice lacking GDE2, a six-transmembrane protein that...

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Main Authors: Sabharwal, Priyanka, Lee, Changhee, Park, Sungjin, Rao, Meenakshi, Sockanathan, Shanthini
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183458/
https://ncbi.nlm.nih.gov/pubmed/21943603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2011.07.028
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