Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy

Fluorescent ligands for the heat shock protein 90 (Hsp90) were synthesized containing either fluorescein isothiocyanate (FITC), 4-nitrobenzo[1,2,5]oxadiazole (NBD) or the red shifted dye sulforhodamine 101 (Texas Red) conjugated to PU-H71. Two of the compounds, PU-H71-FITC2 (9) and PU-H71-NBD1 (8),...

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Main Authors: Taldone, Tony, Gomes-DaGama, Erica M., Zong, Hongliang, Sen, Siddhartha, Alpaugh, Mary, Zatorska, Danuta, Alonso, Raul, Guzman, Monica L., Chiosis, Gabriela
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175602/
https://ncbi.nlm.nih.gov/pubmed/21802945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.07.026
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