Inflammasome is a central player in the induction of obesity and insulin resistance

Inflammation plays a key role in the pathogenesis of obesity. Chronic overfeeding leads to macrophage infiltration in the adipose tissue, resulting in proinflammatory cytokine production. Both microbial and endogenous danger signals trigger assembly of the intracellular innate immune sensor Nlrp3, r...

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Xehetasun bibliografikoak
Egile Nagusiak: Stienstra, Rinke, van Diepen, Janna A., Tack, Cees J., Zaki, Md. Hasan, van de Veerdonk, Frank L., Perera, Deshani, Neale, Geoffrey A., Hooiveld, Guido J., Hijmans, Anneke, Vroegrijk, Irene, van den Berg, Sjoerd, Romijn, Johannes, Rensen, Patrick C. N., Joosten, Leo A. B., Netea, Mihai G., Kanneganti, Thirumala-Devi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174591/
https://ncbi.nlm.nih.gov/pubmed/21876127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100255108
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