TLR-3 is Present in Human Adipocytes, but Its Signalling is Not Required for Obesity-Induced Inflammation in Adipose Tissue In Vivo

Innate immunity plays a pivotal role in obesity-induced low-grade inflammation originating from adipose tissue. Key receptors of the innate immune system including Toll-like receptors-2 and -4 (TLRs) are triggered by nutrient excess to promote inflammation. The role of other TLRs in this process is...

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Pubblicato in:PLoS One
Autori principali: Ballak, Dov B., van Asseldonk, Edwin J. P., van Diepen, Janna A., Jansen, Henry, Hijmans, Anneke, Joosten, Leo A. B., Tack, Cees J., Netea, Mihai G., Stienstra, Rinke
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395029/
https://ncbi.nlm.nih.gov/pubmed/25867514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123152
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